Impact Of Evidence-Based Nursing On Clinical Outcomes And Safety In Diverse Healthcare Settings: A Multicentric Analysis

Abstract

Evidence-based practice has emerged as the cornerstone of contemporary nursing, fundamentally transforming healthcare delivery across diverse settings. This multicentric analysis examined the impact of evidence-based nursing interventions on clinical outcomes and patient safety parameters across 288,581 healthcare facilities spanning 32 countries. The study employed a comprehensive methodology integrating systematic reviews, meta-analyses, and multicentric observational data from 2020-2023. Results demonstrated significant improvements in patient safety indicators, including reduction in mortality rates from 7.75% to 6.27%, decrease in healthcare-associated infections by 34.2-49%, reduction in hospital readmissions from 21.5% to 17.8%, and improvement in medication error rates by 30-70%. Evidence-based nursing implementation correlated with shortened hospital stays from 8.5 to 6 days and enhanced patient satisfaction scores by 5-61%. The analysis reveals that evidence-based nursing practices substantially improve clinical outcomes, reduce adverse events, and optimize resource utilization. These findings underscore the critical importance of systematic integration of research evidence into clinical nursing practice for achieving superior patient safety and healthcare quality outcomes across varied institutional settings.